Advances in lipid research. Vol. 15 by Rodolfo Paoletti, Dr. David Kritchevsky PDF

By Rodolfo Paoletti, Dr. David Kritchevsky

ISBN-10: 0120249154

ISBN-13: 9780120249152

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This adaptation seems to counteract changes in rates of physiological and biochemical functions, such as permeability and transport, that a change in temperature may bring about (for a review, see Fourcans and Jain, 1974). Some clues to the significance of these variations in membrane fatty acids have come from studies on model membranes. Generally speaking, the temperature range of the gel-to-liquid crystalline phase transition of these membrane lipids encompasses the growth temperature of the organism, so that lipids in both gel and liquid crystalline phases are present.

49). 8. Regions of highly ordered but inhomogeneous arrangements, such as domains or plates in bilayer, could be prime movers for processes involving membrane fusion. , see Jain and Wu, 1977). Existence of domains as prelude to fusion has also been demonstrated in heliozoan axopods (Bárdele, 1976). A discussion of the functional significance of such "frozen" membrane domains is also presented by this paper. C. SOME CONSEQUENCES AND PREDICTIONS The behavior of a phase containing "clusters" of structurally distinct polymorphs (the plates) would be quite characteristic.

Such a redistribution of plates could also be brought about by other membrane components (Edelman et al, 1973; Berlin et al, 1974; Taylor et al, 1971; Wessels et al, 1971), or by cytoplasmic effectors of intramembrane mobility (Edelman et al, 1973; Berlin et al, 1974; Taylor et al, 1971; Wessels et al, 1971), or by a change in membrane surface electrostatic profile (Stackpole et al, 1972). In any event the effective local membrane viscosity will be determined by relative distribution of lipid in plates and in disorganized regions.

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Advances in lipid research. Vol. 15 by Rodolfo Paoletti, Dr. David Kritchevsky


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